从“One Health”视角应对抗微生物药物耐药性Response to Antimicrobial Resistance from the Perspective of "One Health"
王浩然,王琳,刘俊辉,王娟,赵格,刘娜,张喜悦,王君玮,曲志娜
摘要(Abstract):
作为一场席卷全球的卫生危机,抗生素长期使用所带来的抗微生物药物耐药性(antimicrobial resistance,AMR)日趋严重,耐药病原菌、多重耐药菌、“超级细菌”等问题逐步成为公共卫生、畜牧兽医、环境卫生等领域共同面对的严峻挑战。近年来,随着“One Health”理念的兴起和探索实践,该理念逐步成为应对AMR挑战、实现人-动物-环境共同健康的共识。本文从“One Health”视角看待AMR问题,综述了“One Health”及AMR的发展历程,总结了国内外应用“One Health”理念遏制AMR问题的方法策略,提出了应对AMR问题的未来发展方向,为共同应对AMR挑战提供了参考。
关键词(KeyWords): One Health;细菌;耐药性;应对策略
基金项目(Foundation): 国家重点研发计划项目(2022YFC2303900);; 青岛市科技惠民示范引导专项(21-1-4-ny-11-nsh);; 中国动物卫生与流行病学中心创新基金项目(DW2021001-18)
作者(Author): 王浩然,王琳,刘俊辉,王娟,赵格,刘娜,张喜悦,王君玮,曲志娜
参考文献(References):
- [1]孙双勇,王蒙蒙,李丽,等.抗生素耐药与抗生素新药开发的研究进展[J].现代药物与临床,2022,37(2):221-229.
- [2]斯日古楞,刘欢欢,周越,等.细菌耐药所致患者健康和经济负担的研究进展[J].世界临床药物,2022,43(11):1399-1404.
- [3]王允超,路建彪,孙秋艳,等.家禽业如何面对“后抗生素时代”的挑战[J].山东家禽,2004(7):24-26.
- [4]TAPPE D,FROSCH M.Rudolf Virchow and the recognition of alveolar echinococcosis,1850s[J].Emerging infectious diseases,2007,13(5):732-735.
- [5]KARESH W.William Karesh:championing “One Health"[J].Bulletin of the World Health Organization,2020,98(10):652-653.
- [6]姜秋月.生态翻译理论视域下科技术语“One Health”的汉译研究[D].南京:南京农业大学,2016.
- [7]周晓农.以全健康理念推进人兽共患病预防与控制[J].中国寄生虫学与寄生虫病杂志,2022,40(1):12-19.
- [8]PAUL R B.Antibiotics:the exploitation of microbial antagonisms is having a challenging impact on medicine and society[J].Science,1959,129(3361):1457-1465.
- [9]JEVONS M P."Celbenin":resistant Staphylococci[J].British medical journal,1961,1(5219):124-125.
- [10]SWANN M.Report of the joint committee on the use of antibiotics in animal husbandry and veterinary medicine[R].London:Her Majesty's Stationery Office,1969.
- [11]STUART B L.Emergence of antibiotic-resistant bacteria in the Intestinal Flora of farm inhabitants[J].The journalof infectious diseases,1978,137(5):688-690.
- [12]潘志明,焦新安,刘学贤,等.鸡白痢沙门氏菌耐药性的变化趋势[J].中国预防兽医学报,1999(4):66-68.
- [13]MA L,XIA Y,LI B,et al.Metagenomic assembly reveals hosts of antibiotic resistance genes and the shared resistome in pig, chicken,and human feces[J].Environmental science&technology,2016,50(1):420-427.
- [14]LIU Z,KLUMPER U,SHI L,et al.From pig breeding environment to subsequently produced pork:comparative analysis of antibiotic resistance genes and bacterial community composition[J].Frontiers in microbiology,2019,10(10):43.
- [15]王会生,张佩,杜逢艳,等.禁抗前后规模鸡场环境中金黄色葡萄球菌和大肠杆菌对15种抗菌药的敏感性比较[J].中国动物检疫,2021,38(1):115-119.
- [16]MIAO E A,MILLER S I.Bacteriophages in the evolution of pathogen-host interactions[J].Proceedings of the National Academy of Sciences,1999,96(17):9452-9454.
- [17]WHITMEE S,HAINES A,BEYRER C,et al.Safeguarding human health in the Anthropocene epoch:report of The Rockefeller Foundation-Lancet Commission on planetary health[J].The lancet,2015,386(10007):1973-2028.
- [18]MURRAY C J L,IKUTA K S,SHARARA F,et al.Global burden of bacterial antimicrobial resistance in2019:a systematic analysis[J].The lancet,2022,399(10325):629-655.
- [19]Centers for Disease Control and Prevention.Antibiotic resistance threats in the United States,2013[EB/OL].(2013-04-23)[2023-04-03].https://www.cdc.gov/drugresistance/pdf/ar-thre ats-2013-508.pdf.
- [20]中欧合作遏制细菌耐药[J].中国医药导刊,2012,14(3):488.
- [21]World Health Organization.Quadripartite welcomes new political commitments in fight against antimicrobial resistance[EB/OL].(2022-11-25)[2023-04-03].https://www.who.int/news/item/25-11-2022-quadripartitewelcomes-new-political-commitments-in-fight-againstantimicrobial-re sistance.
- [22]路平,张衍海,王君玮,等.世界动物卫生组织第五战略规划研究及政策建议[J].中国家禽,2012,34(4):5-7.
- [23]MENICHETTI F,FALCONE M,LOPALCO P,et al.The GISA call to action for the appropriate use of antimicrobials and the control of antimicrobial resistance in Italy[J].International journal of antimicrobial agents,2018,52(2):127-134.
- [24]World Organization for Animal Health.Aiming for a more prudent use of antimicrobials:the progress of the animal health sector[Z].Paris:WOAH,2022.
- [25]TAYLOR P,REEDER R.Antibiotic use on crops in low and middle-income countries based on recommendations made by agricultural advisors[J].CAB I agriculture and bioscience,2020(1):1-14.
- [26]Fera Science Ltd.Review of antibiotic use in crops,associated risk of antimicrobial resistance and research gaps[EB/OL].[2023-04-03].https://www.food.gov.uk/site s/default/files/media/docume nt/review-of-antibioticuse-in-crops_0.pdf.
- [27]United Nations Environment Programme.Bracing for superbugs:strengthening environmental action in the one health response to antimicrobial resistance[EB/OL].(2023-02-07)[2023-04-03].https://www.unep.org/re source s/superbugs/enviromnental-action.
- [28]施雱.从二元对立到“同一健康”:美国关于抗生素认知的演变[J].安徽史学,2022(4):103-111.
- [29]Centers for Disease Control and Prevention.National action plan for combating antibiotic-re sistant bacteria[EB/OL].(2022-05-13)[2023-04-03].https://aspe.hhs.gov/reports/carb-year-5-report.
- [30]刘跃华,韩萌,冉素平,等.欧洲应对抗生素耐药问题的治理框架及行动方案[J].中国医院药学杂志,2019,39(3):219-223.
- [31]DE CASTANEDA R R,GARRISON A,HAEBERLI P,et al.First global flipped classroom in one health:from MOOCs to research on real world challenges[J].One health,2018,5:37-39.
- [32]Food Standards Agency.Modelling framework to quantify the risk of AMR exposure via food products-example of chicken and lettuce[EB/OL].(2022-04-07)[2023-04-03].http s://www.food.gov.uk/re searc h/antimicrobialre sistance/modelling-frame work-to-quantify-the-risk-ofamr-expo sure-via-food-pro ducts-example-of-c hicken-andlettuce.
- [33]GODIJK N G,BOOTSMA M C J,BONTEN M J M.Transmission routes of antibiotic resistant bacteria:a systematic review[J].BMC infectious diseases,2022,22(1):1-15.
- [34]中英全球卫生支持项目办公室.政策简报第38期:中国应更加主动地参与抗生素耐药性全球治理[EB/OL].(2018-07-31)[2023-04-03].https://cps.nhc.gov.cn/ghsp/xmcc/201807/5f5767ad472749e58f841302d276b214.shtml.
- [35]郭凯旋,王湘如,赵月,等.我国动物源细菌耐药性监测及预警的研究进展[J].中国兽药杂志,2021,55(4):79-85.
- [36]关于印发遏制细菌耐药国家行动计划(2016—2020年)的通知:国卫医发[2016] 43号[EB/OL].(2016-08-25)[2023-04-03].https://www.gov.cn/xinwen/2016-08/25/content_5102348.htm.
- [37]关于印发遏制微生物耐药国家行动计划(2022-2025年)的通知:国卫医函[2022] 185号[EB/OL].(2022-10-25)[2023-04-03].http://www.hunan.gov.cn/zqt/zcsd/202210/t20221031 29111467.html.
- [38]GREEN A.Zimbabwe post-Mugabe era:reconstructing a health sy stem[J].The lancet,2018,391(10115):17-18.
- [39]LAING R,RUREDZO R.The essential drugs programme in Zimbabwe:new approaches to training[J].Health policy and planning,1989,4(3):229-234.
- [40]Food and Agriculture Organization.Mongolia at the crossroads for antibiotic re sistance[EB/OL].(2019-11-22)[2023-04-03].https://www.fao.org/mongolia/news/detailevents/m/c/12 5 2194/.
- [41]Codex Alimentarius.Mongolia planning to assess national antimicrobial resistance(AMR)surveillance system[EB/OL].(2022-06-29)[2023-04-03].https://www.fao.org/fao-who-codexalimentarius/new s-and-events/newsdetails/en/c/1539859.
- [42]WOOLHOUSE M,FARRAR J.Policy:an inte rgovernmental panel on antimic robial re sistance[J].Nature,2014,509(7502):555-557.
- [43]BLAUWKAMP T A,THAIR S,ROSEN M J,et al.Analytical and clinical validation of a microbial cell_free DNA sequencing test for infectious disease[J].Nature microbiology,2019,4(4):663-674.
- [44]CANI?A M,MANAGEIRO V,ABRIOUEL H,et al.Antibiotic resistance in foodborne bacteria[J].Trends in food science&technology,2019,84:41-44.